Rheumatoid arthritis (RA) is a chronic autoimmune disease that primarily affects the joints, causing inflammation, pain, and eventually joint damage. The cause of RA is thought to be a combination of genetic, environmental and lifestyle factors, such as smoking and obesity. Approximately 18 million people worldwide suffer from RA, with a higher prevalence in women, especially those over the age of 55. The disease can have a significant impact on daily activities and quality of life, leading to physical limitations and psychological distress.
The detection of rheumatoid arthritis (RA) typically involves the identification of specific biomarkers in the blood. Key markers include C-reactive protein (CRP) and rheumatoid factor (RF), which indicate inflammation and immune response, respectively. In addition, anti-citrullinated protein antibodies (anti-CCP) are highly specific for RA and play an important role in early diagnosis. Elevated levels of these biomarkers not only indicate the presence of RA, but also its severity, helping healthcare providers develop effective treatment plans.
To streamline this process, rapid tests for RA have been introduced to enable earlier diagnosis. These point-of-care tests rapidly measure CRP and RF levels from small blood samples, providing results within minutes for timely intervention. Moreover, advanced technologies such as multiplex assays can detect multiple biomarkers simultaneously, significantly improving diagnostic accuracy and efficiency. This integrated approach enables healthcare professionals to initiate appropriate treatment earlier, ultimately improving patient outcomes.
Preventing and treating RA requires a multifaceted approach. Including lifestyle changes, such as maintaining a healthy weight, engaging in regular physical activity and avoiding smoking, reduce the risk of developing RA. Once diagnosed, treatment usually includes non-steroidal anti-inflammatory drugs (NSAIDs), disease-modifying anti-rheumatic drugs (DMARDs) and biologics to control symptoms and mitigate disease progression. Early diagnosis and intervention are critical to minimize joint damage and improve long-term prognosis.